A new clinical study from the US shows a reduction in contamination risk of 97% when using a closed system transfer device (CSTD) to administer hazardous drugs.

The US study* involved 13 cancer centres across the United States and the findings demonstrated that the CSTD reduced surface contami­nation by cyclophosphamide and fluorouracil during compounding and simulated administration.

When the hospitals did not use a CSTD, the level of antimitotic contamination during administration was 78%. This rate decreases to 2.6% when using a CSTD, which represents a reduction of nearly 97% in contamination rate. Furthermore, par­ticipants reported that the CSTD was easy to use.


  • Bartel, S et al Multicenter evaluation of a new closed system drug-transfer device in reducing surface contamination by antineoplastic hazardous drugs American Journal of Health-System Pharmacy 2018 Volume 75

Download the paper in full from http://www.qimono.co.uk/papers-supporting-cstd/